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</center><p>ESTEBAN et al. Prolonged mechanical ventilation increases the risk of pneumonia, barotrauma, tracheal injuries, and musculoskeletal onditioning. We aimed to describe the epidemiology,  Weaning from mechanical ventilation is the process of reducing ventilatory support, ulti-matelyresultinginapatientbreathingspontan-eously and being extubated. This process  This review provides a broad encompassing view of weaning classification, causes of weaning failure, and evidence behind weaning predictors and weaning modes In The Lancet Respiratory Medicine, Tài Pham and colleagues1 report the results of the WEAN SAFE study, aiming to describe the epidemiology, management, timings, risk for  1) What is known about the epidemiology of weaning problems? [7] demonstrated that mortality increases with increasing duration of mechanical ventilation, in part because of complications of prolonged mechanical ventilation, especially ventilator-associated pneumo-nia and airway trauma [8] Mechanical ventilation is an established supportive treatment for patients with various forms of respiratory failure. We aimed to describe the epidemiology, management, timings, risk for Weaning from mechanical ventilation. This was originally delivered at set volumes and rates Mechanical ventilation has gone through a dramatic evolution over a relatively short space of time. At the same time, delayed weaning is Background: Current management practices and outcomes in weaning from invasive mechanical ventilation are poorly understood. Current management practices and outcomes in weaning from invasive mechanical ventilation are poorly understood. After the Copenhagen polio epidemic in, negative pressure ‘iron lungs’ were replaced by intermittent positive pressure ventilation. 3) What is the usual process of initial weaning from in the weaning process represents–50% of the total duration of mechanical ventilation [4–7]. Despite the widespread use and clear benefits of mechanical ventilation, it is not a risk-free intervention. 2) What is the pathophysiology of weaning failure?</p></translate>
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