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</center><p>[1][2] Los síntomas del síndrome de CREST se asocian con la forma generalizada de la enfermedad de la esclerosis sistémica (esclerodermia) Systemic scleroderma (SSc) is a multisystem disease with microvascular abnormalities, autoimmune disorders, excessive. El síndrome CREST (calcinosis, fenómeno de Raynaud, alteraciones de la motilidad esofágica, esclerodactilia y telangiectasias) es una forma limitada de esclerodermia en  CREST syndrome is a localized variant of systemic sclerosis characterized by the presence of calcinosis, Raynaud’s phenomenon, esophageal dysmotility, sclerodactyly and  CREST syndrome is part of the heterogeneous scleroderma group of autoimmune diseases that cause thickening, hardening and tightening of the connective tissue in different parts  systemic sclerosis affects only face and distal extremities (arms, forearms), CREST syndrome is a form of limited systemic sclerosis; and in the scleroderma without  El síndrome CREST es una enfermedad del tejido conectivo en que hay problemas en la piel, los vasos sanguíneos, los músculos esqueléticos, y los órganos internos. In our case, a year-old male was admitted for a nonhealing lower extremity ulcer that El síndrome de CREST es una enfermedad autoinmunitaria. [1] [2] Los CREST. collagen production and deposition, and ﬁ brosis of the skin and internal CREST syndrome is a localized variant of systemic sclerosis characterized by the presence of calcinosis, Raynaud’s phenomenon, esophageal dysmotility, sclerodactyly and telangiectasia. Eso significa que el sistema inmunitario no está funcionando a uadamente, entonces se ataca a sí mismo. Suele atacar a las personas de entreyaños de edad El síndrome CRESTes una enfermedad del tejido conectivo en que hay problemas en la piel, los vasos sanguíneos, los músculos esqueléticos, y los órganos internos. Biopsy of the skin reveals dermal fibrosis like the changes seen in the thickened skin of Systemic Sclerosis Resumen. We present a rare case of CREST syndrome in a white male with no personal or family history of autoimmune disease. CREST syndrome, also known as limited or localized scleroderma, is a diffuse connective tissue disease which is differentiated by changes in the skin and subcutaneous tissue, blood vessels, skeletal muscles, and internal organs. Este problema de salud es infrecuente y es más probable que aparezca en mujeres.</p></translate>
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