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</center><p>The obvious • review current evidence on combination therapy with antimalarial drugs recommend the minimal criteria for selection and use of combination therapies of antimalarial drugs in different epidemiological settings select appropriate combinations for use, particularly in African countries Currently there are four major drug classes to treat malaria, which contain quinoline-based compounds, antifolates, artemisinin derivatives, and  protocol for assessing antimalarial drug efficacy in high transmission areas. The antimalarials in common use come from the following classes of compounds: the quinolines (chloroquine, quinine, mefloquine, amodiaquine, primaquine), the antifolates  This document is a PDF generated from the WHO Guidelines for malaria hosted on the MAGICapp online platform:/guideline/ Each time the  Outline the contraindications and toxicity of antimalarial drugs. Since then, WHO has regularly updated the therapeutic efficacy protocol for high transmission areas Download reference work entry PDF. Currently available antimalarial drugs can be classified into four broad categories according to their chemical structures and modes of actionArylamino alcohol compounds: quinine, quinidine, chloroquine, amodiaquine, mefloquine, halofantrine, piperaquine, and lumefantrine Antimalarial treatment with a single medicine: either a single active compound or a synergistic combination of two compounds with related mechanisms of action Antimalarial drugs are used for the treatment and prevention of malaria infection. Most antimalarial drugs target the erythrocytic stage of malaria infection, which is the phase of infection that causes symptomatic illness (figure 1) To guide malaria treatment appropriately, it is important to identify three factors: (1) the infecting Plasmodium species, (2) the clinical status of the patient, and (3) the drug susceptibility of the infecting parasites (the geographic area from where the infection was acquired from and any previous antimalarial medications). Explain the importance of antimalarial  Classes of antimalarial drugs. Review the appropriate follow-up and monitoring of antimalarial agents.</p></translate>
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