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</center><p>Antithrombotics include medications classi-fied as anticoagulants or antiplatelet agents (APAs) Patients enrolled in an AMS have a reduced risk of develop-ing pulmonary embolism (PE Direct oral anticoagulants (DOACs)—dabigatran (Pradaxa), rivaroxaban (Xarelto), apixaban (Eliquis), edoxaban (Savaysa), and betrixaban (Bevyxxa) are anticoagulation pharmacotherapy used for the prevention of thrombosis in several cardiovascular contextsDOACs are categorized intomain classes: oral direct factor Xa inhibitors (ie, rivaroxaban, apixaban, edoxaban, and betrixaban) and The guideline panel assessed the certainty in the supporting evidence and developed and graded the recommendations following the GRADE approachThe overall guideline-development process, including funding of the work, panel formation, management of conflicts of interest, internal and external review, and organizational approval, was The panel followed best practice for guideline development recommended by the National Academy of Medicine (formerly Institute of Medicine) and the Guidelines International Network (GIN)The panel used the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach to assess the certainty in the evidence and Antithrombotic therapy is used to reduce the risk of thromboembolic events in patients with conditions such as atrial fibrillation (AF), acute coronary syndrome (ACS), deep vein thrombosis (DVT), hypercoagulable states, and endoprostheses. Antithrombotic therapy is used to reduce the risk of thromboembolic events  Recommendations for Anticoagulation for AF in Patients With VHD Referenced studies  A comprehensive guide for anticoagulation practitioners, based on evidence-based COAGULATION MANAGEMENT SERVICES (AMS)For patients receiving anticoagulation therapy for treatment of VTE, the ASH guideline panel suggests using specialized AMS care (where available) rather than care provided by the pati. Anticoagulation therapy is recommended for preventing, treating, and reducing the  American Society of Hematology guidelines for management of venous  guidelines. nt’s regular health care provider.</p></translate>
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